Biosecurity safeguards for emerging technologies
In collaboration with the Nuclear Threat Initiative and the International Biosecurity and Biosafety Initiative for Science, we design tools to detect and prevent the misuse of emerging technologies for manipulating biology.
Linking genotype to phenotype
Building methods to accurately identify parts of a pathogen genome that contribute to pathogenicity, designing accurate tools to detect novel high-risk pathogen strains using these genetic signatures.
Improving our response to infectious disease threats
Naturally emerging threats and common diseases also pose an ongoing threat to human health and flourishing. Computer science approaches can be employed to enhance or rethink our approaches to responding to infectious disease threats.
Understanding how high-risk pathogen strains emerge
Which factors differentiate successful and unsuccessful novel high-risk pathogen strains? Can understanding these factors help us better design community and public health interventions to make success less likely?
The Wheeler lab is jointly situated in the Institute of Microbiology and Infection and the School of Computer Science at the University of Birmingham. The lab works across disciplines and focuses on the development and application of computational tools for enhancing the genomic surveillance of emerging biological threats. Main research themes in the lab are:​